Invitrogen™ H3K18cr Recombinant Rabbit Monoclonal Antibody (21H13L11)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 703472

Catalog No. 70-347-2

Description

This antibody is predicted to react with Rat, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Specifications

• Antigen: H3K18cr
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P68431, P68433
• Gene Symbols: H3C1, HIST1H3A
• Immunogen: Peptide corresponding to human H3.1crK18 [aa14-aa25].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Clone: 21H13L11
• Conjugate: Unconjugated
• Gene: H3C1
• Gene Alias: Crotonyl-Histone H3.1 K18; Crotonyl-Histone H3.1 Lys18; H3 histone family, member A; H3.1-221; H3.1-291; H3.1-I; H3/A; H3a; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3g; H3h; H3i; HIST1H3A; HIST1H3B; HIST1H3D; HIST1H3E; HIST1H3F; Hist1h3g; Hist1h3h; Hist1h3i; HIST1H3J; histone 1, H3a; histone cluster 1, H3a; histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 0, 360198, 8350
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov