Invitrogen™ H3K27cr Recombinant Rabbit Monoclonal Antibody (RM401)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA538669

Catalog No. PIMA538669

Description

H3K27cr Recombinant Monoclonal Antibody for Western Blot, DB

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: H3K27cr
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
• Gene Accession No.: P68431
• Gene Symbols: H3C1
• Immunogen: A crotonyl-peptide corresponding to Crotonyl-Histone H3 (Lys27).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Dot Blot, Western Blot
• Clone: RM401
• Conjugate: Unconjugated
• Gene: H3C1
• Gene Alias: H3 histone family, member A; H3 K27CR; H3 Lys27 Cr; H3.1-221; H3.1-291; H3.1-I; H3/A; H3a; H3C1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3g; H3h; H3i; H3Lys27Cr; Hist1h3a; HIST1H3B; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; histone 1, H3a; histone cluster 1, H3a; Histone H3 K27 Cr; Histone H3 Lys27 Cr; histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8350
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid