Invitrogen™ H3R8me1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110611

Catalog No. PIPA5110611

Description

Immunogen sequence: TARKS.

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post tranlationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: H3R8me1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H3-4
• Gene Alias: H3 histone family, member T; H3.4; H3/g; H3/t; H3FT; H3t; HIST3H3; histone 3, H3; histone cluster 3, H3; histone H3.1t
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8290
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Dot Blot, ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Immunoprecipitation, Western Blot
• Concentration: 0.45 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: Q16695
• Gene Symbols: H3-4
• Immunogen: A synthetic monomethylated peptide around R8 of human histone H3 (NP_0035201).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG