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Invitrogen™ H3R8me2s Polyclonal Antibody
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Catalog No. PIPA5114683
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PIPA5114683 100 μL
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Catalog No. PIPA5114683 Supplier Invitrogen™ Supplier No. PA5114683
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Di-Methyl-Histone H3 only when methylated at Arg8.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen H3R8me2s
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene H3C15
Gene Accession No. P84228, Q71DI3
Gene Alias dimethyl H3; di-methyl H3; dimethyl histone H3; di-methyl histone H3; H3; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3/l; H3/M; H3/n; H3/o; H3-143; H3-53; H3-614; H3Arg8me2s; H3b; H3-B; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F2; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; HIST1H3A; Hist1h3b; Hist1h3c; Hist1h3d; HIST1H3E; Hist1h3f; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; histone 1, H3b; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; histone cluster 1, H3b; histone cluster 2, H3a; histone cluster 2, H3c; histone cluster 2, H3c2; histone cluster 2, H3c2, pseudogene; histone H3.1; Histone H3.2; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; histone H3/m; Histone H3/o; M32461
Gene Symbols H3C15, H3C2
Host Species Rabbit
Immunogen A synthetic methylated peptide derived from human Di-Methyl-Histone H3 around the methylation site of Arg8.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 319150, 333932, 8358, 97114
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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