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Invitrogen™ H4K12ac Polyclonal Antibody
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Catalog No. PIPA5114694
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PIPA5114694 100 μL
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Catalog No. PIPA5114694 Supplier Invitrogen™ Supplier No. PA5114694
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Acetyl-Histone H4 only when acetylated at Lys12.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen H4K12ac
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene H4C1
Gene Accession No. P62805, P62806
Gene Alias acetyl Histone H4; Acetyl-H4 K12; Acetyl-H4 Lys12; Acetyl-Histone H4 K12; Acetyl-Histone H4 Lys12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K12ac; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4C11; H4c12; H4C13; H4c14; H4C15; H4c2; H4c3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K12; H4K12a; H4Lys12ac; H4M; HIST1H4; Hist1h4a; HIST1H4B; Hist1h4c; Hist1h4d; HIST1H4E; HIST1H4F; HIST1H4H; Hist1h4i; Hist1h4j; HIST1H4K; HIST1H4L; Hist1h4m; Hist2h4; Hist2h4a; HIST2H4B; HIST4H4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone cluster 2, H4; histone cluster 2, H4a; Histone Cluster 4; histone cluster 4, H4; histone family member; histone H4; Histone H4 acetyl; Histone H4A; Histone H4K12; Histone H4K12ac; histone IV, family 2; X04652
Gene Symbols H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9
Host Species Rabbit
Immunogen A synthesized peptide derived from human Histone H4(Accession P62805), corresponding to amino acid residues M1-Q28.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 121504, 319158, 326619, 326620, 8294, 8359, 8363, 8366, 8367, 8370, 97122
Target Species Human, Mouse, Monkey, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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