Invitrogen™ H6PD Polyclonal Antibody

Catalog No.	Quantity
PIPA592977	100 μL

Catalog No. PIPA592977 Supplier Invitrogen™ Supplier No. PA592977

Description

Rabbit Polyclonal Antibody

Immunogen sequence: QELQGHVSII LLGATGDLAK KYLWQGLFQL YLDEAGRGHS FSFHGAALTA PKQGQELMAK ALESLSCPKD MAPSHCAEHK DQFLQLSQYR QLKTAEDYQA LNKDIEAQLQ HAGLREAGRI FYFSVPPFAY EDIARNINSS CRPGPGAWLR VVLEKPFGHD HFSAQQLATE LGTFFQEEEM Y; Positive Samples: Mouse liver, Mouse kidney; Cellular Location: Endoplasmic reticulum lumen.

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a type 2 salivary cysteine peptidase inhibitor. The protein is an S-type cystatin, based on its high level of expression in saliva, tears and seminal plasma. The specific role in these fluids is unclear but antibacterial and antiviral activity is present, consistent with a protective function.

Specifications

• Antigen: H6PD
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 1.23 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: H6PD
• Gene Accession No.: O95479, Q8CFX1
• Gene Alias: 6PGL; 6-phosphogluconolactonase; AI785303; CORTRD1; EGK_00198; G6PD, H form; G6pd1; G6PDH; GDH; GDH/6PGL endoplasmic bifunctional protein; glucose 1- dehydrogenase; glucose 1-dehydrogenase; glucose dehydrogenase; glucose dehyrogenase; Glucose-6-phosphate dehydrogenase; glucose-6-phosphate dehydrogenase 1; glucose-6-phosphate dehydrogenase, salivary; Gpd1; Gpd-1; H6pd; H6pdh; hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase
• Gene Symbols: H6PD
• Host Species: Rabbit
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human H6PD (NP_0042762).
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100198, 298655, 9563
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG