Invitrogen™ HABP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA563225

Catalog No. PIPA563225

Description

Immunogen sequence: RGGPGNRVFD AFDQRGKREF ERYGGNDKIA VRTEDNMGGC GVRTWGSGKD TSDVEPTAPM EEPTVVEESQ GTPEEESPAK VPE Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 75%.

RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594). Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre-mRNA splicing regulation (PubMed:19523114). Binds (via C-terminus) to poly(U) RNA (PubMed:19523114). Involved in mRNA translation regulation, probably at the initiation step (PubMed:21771594). Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). [UniProt].

Specifications

• Antigen: HABP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HABP4
• Gene Alias: 4933413D03Rik; 4933428J01Rik; chromodomain helicase DNA binding protein 3 interacting protein; habp4; hyaluronan binding protein 4; Hyaluronan-binding protein 4; hyaluronic acid binding protein 4; Hyaluronic acid-binding protein 4; hyaluronic acid-binding protein 4 (intracellular); IHABP4; IHABP-4; intracellular antigen detected by monoclonal antibody Ki-1; intracellular hyaluronan-binding protein 4; intracellular hyaluronan-binding protein p57; Ki-1/57; ki-1/57 intracellular antigen; SERBP1L
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22927
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5JVS0
• Gene Symbols: HABP4
• Immunogen: Recombinant protein corresponding to Human HABP4. Recombinant protein control fragment (Product #RP-101784).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG