HACE1 Mouse anti-Human, Clone: OTI4E10, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF810060
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCOE3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.
|Full length human recombit protein of human HACE1 produced in HEK293T cell.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|-20° C, Avoid Freeze/Thaw Cycles|
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