Invitrogen™ HADHB Polyclonal Antibody

Catalog No.	Quantity
PIPA583376	100 μL

Catalog No. PIPA583376 Supplier Invitrogen™ Supplier No. PA583376

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LRDFMYVSQD PKDQLLLGPT YATPKVLEKA GLTMNDIDAF EFHEAFSGQI LANFKAMDSD WFAENYMGRK TKVGLPPLEK FNNWGGSLSL G Highest antigen sequence indentity to the following orthologs: Rat - 96%, Mouse - 96%.

This gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Mutations in this gene result in trifunctional protein deficiency. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: HADHB
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: HADHB
• Gene Accession No.: P55084, Q60587, Q99JY0
• Gene Alias: 2-enoyl-Coenzyme A (CoA) hydratase, beta subunit; 3-ketoacyl-CoA thiolase; 3-ketoacyl-Coenzyme A (CoA) thiolase of mitochondrial trifunctional protein, beta subunit; 4930479F15Rik; acetyl-CoA acyltransferase; bet; Beta-ketothiolase; ECHB; HADHB; hydroxyacyl-Co; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta aubunit; hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit; mitochondrial trifunctional protein, beta subunit; MSTP029; MTPB; TP-BETA; trifunctional enzyme subunit beta, mitochondrial
• Gene Symbols: HADHB
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human HADHB. Recombinant protein control fragment (Product #RP-96092).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 171155, 231086, 3032
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG