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Tocris Bioscience™ Halofuginone hydrobromide
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Catalog No. 199350
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

High affinity competitive prolyl-tRNA synthetase inhibitor

Halofuginone hydrobromide is a high affinity competitive prolyl-tRNA synthetase inhibitor (Ki = 18.3 nM). Blocks expression of MMP2. Inhibits ECM invasion in vitro and lung metastasis by bladder cancer cells in mice. Inhibits the development of Th17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway. Also antiparasitic.

Specifications

Chemical Name or Material (2R*,3S*)-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidinyl)-2-oxopropyl]-4-3H-quinazolinone hydrobromide
CAS 64924-67-0
Assay Percent Range >98%
Quantity 50 mg
Molecular Formula C16H17BrClN3O3.HBr
Formula Weight Observed MW: 495.59
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