Invitrogen™ HAMP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576075

Catalog No. PIPA576075

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

Specifications

• Antigen: HAMP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HAMP
• Gene Alias: HAMP; Hamp1; HEPC; Hepc1; Hepc20; Hepc25; Hepcidin; hepcidin antimicrobial peptide; hepcidin antimicrobial peptide 1; Hepcidin-20; Hepcidin-25; HFE2B; LEAP1; LEAP-1; liver-expressed antimicrobial peptide 1; PLTR; Putative liver tumor regressor; UNQ487/PRO1003
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57817
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P81172
• Gene Symbols: HAMP
• Immunogen: Recombinant full length Human HAMP.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG