Invitrogen™ HAMP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590884

Catalog No. PIPA590884

Description

Immunogen sequence: MALSSQIWAA CLLLLLLLAS LTSGSVFPQQ TGQLAELQPQ DRAGARASWM PMFQRRRRRD THFPICIFCC GCCHRSKCGM CCKT; Positive Samples: MDA-MB-435.

HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

Specifications

• Antigen: HAMP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HAMP
• Gene Alias: HAMP; Hamp1; HEPC; Hepc1; Hepc20; Hepc25; Hepcidin; hepcidin antimicrobial peptide; hepcidin antimicrobial peptide 1; Hepcidin-20; Hepcidin-25; HFE2B; LEAP1; LEAP-1; liver-expressed antimicrobial peptide 1; PLTR; Putative liver tumor regressor; UNQ487/PRO1003
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57817, 84506
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 4.11 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P81172, Q9EQ21
• Gene Symbols: HAMP
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-84 of human Hepcidin (NP_0669981).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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