Invitrogen™ HAMP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102436

Catalog No. PIPA5102436

Description

Antibody detects endogenous levels of total HAMP.

HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.

Specifications

• Antigen: HAMP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HAMP
• Gene Alias: HAMP; Hamp1; HEPC; Hepc1; Hepc20; Hepc25; Hepcidin; hepcidin antimicrobial peptide; hepcidin antimicrobial peptide 1; Hepcidin-20; Hepcidin-25; HFE2B; LEAP1; LEAP-1; liver-expressed antimicrobial peptide 1; PLTR; Putative liver tumor regressor; UNQ487/PRO1003
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57817, 84506, 84604
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P81172, Q99MH3, Q9EQ21
• Gene Symbols: HAMP
• Immunogen: A synthesized peptide derived from human HAMP(Accession P81172), corresponding to amino acid residues A2-M52.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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