CD3e Hamster anti-Mouse, BUV395, Clone: 500A2, BD Optibuild™

Hamster Monoclonal Antibody

Supplier:  BD Biosciences 740221

Catalog No. BDB740221

Description

The 500A2 monoclonal antibody specifically binds to the 25-kDa ε chain of the T-cell receptor-associated CD3 complex expressed on mouse thymocytes, mature T lymphocytes, and NKT cells. Plate-bound and soluble forms of the 500A2 antibody can activate T cells in vitro . Activation of a mouse T-cell clone by the 500A2 antibody can be blocked by Fab fragments of the GK1.5 anti-CD4 antibody. This suggests that the 500A2 antibody may bind an epitope on CD3e close to a site at which CD4 associates with the T-cell receptor. The 500A2 antibody reportedly does not to crossreact with rat leukocytes.

Specifications

• Antigen: CD3e
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: CD3; CD3 epsilon; Cd3e; CD3ε; T3e
• Host Species: Hamster
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG2 κ

• Applications: Flow Cytometry
• Clone: 500A2
• Conjugate: Brilliant Ultraviolet 395
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse T-cell receptor
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only