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CD3e Hamster anti-Mouse, Brilliant Violet 421, Clone: 500A2, BD Optibuild™

Catalog No. BDB740014 Shop All BD Biosciences Products
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BDB740014 50 μg
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Catalog No. BDB740014 Supplier BD Biosciences Supplier No. 740014
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Description

Hamster Monoclonal Antibody

The 500A2 monoclonal antibody specifically binds to the 25-kDa ε chain of the T-cell receptor-associated CD3 complex expressed on mouse thymocytes, mature T lymphocytes, and NKT cells. Plate-bound and soluble forms of the 500A2 antibody can activate T cells in vitro . Activation of a mouse T-cell clone by the 500A2 antibody can be blocked by Fab fragments of the GK1.5 anti-CD4 antibody. This suggests that the 500A2 antibody may bind an epitope on CD3e close to a site at which CD4 associates with the T-cell receptor. The 500A2 antibody reportedly does not to crossreact with rat leukocytes.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3e
Applications Flow Cytometry
Classification Monoclonal
Clone 500A2
Concentration 0.2mg/mL
Conjugate Brilliant Violet 421
Description CD3; CD3 epsilon; Cd3e; CD3ε; T3e
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Hamster
Immunogen Mouse T-cell receptor
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2 κ
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For Research Use Only

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