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CD61 Hamster anti-Mouse, BUV395, Clone: 2C9.G2, BD Optibuild™

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BDB740229 50 μg
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Catalog No. BDB740229 Supplier BD Biosciences Supplier No. 740229
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Description

Hamster Monoclonal Antibody

The 2C9.G2 monoclonal antibody specifically binds to the integrin β 3 chain (CD61), which associates with the integrin α v chain (CD51) to form the vitronectin receptor and with the α IIb chain (CD41) to form the gpIIb/IIIa complex. Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is also mediated by the binding of α v β 3 integrin or vitronectin receptor to CD31 (PECAM-1). In addition, interaction of the α v β

The antibody was conjugated to BD Horizon™ BUV395 which is part of the BD Horizon Brilliant™ Ultraviolet family of dyes. This dye has been exclusively developed by BD Biosciences to have minimal spillover into other detectors, making it an optimal choice for multicolor flow cytometry. With an Ex Max at 348nm and an Em Max at 395nm, BD Horizon BUV395 can be excited with a 355nm laser and detected with a 379/28 filter.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD61
Applications Flow Cytometry
Classification Monoclonal
Clone 2C9.G2
Concentration 0.2mg/mL
Conjugate Brilliant Ultraviolet 395
Description Itgb3; Integrin beta-3; INGRB3; Platelet glycoprotein IIIa; GP3A; GPIIIa
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Hamster
Immunogen Mouse T-cell Hybridoma 2B4 Vitronectin Receptor
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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