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CD61 Hamster anti-Mouse, Brilliant Violet 605, Clone: 2C9.G2, BD Optibuild™

Hamster Monoclonal Antibody

Manufacturer:  BD Biosciences 740348

Catalog No. BDB740348


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Description

Description

The 2C9.G2 monoclonal antibody specifically binds to the integrin β 3 chain (CD61), which associates with the integrin α v chain (CD51) to form the vitronectin receptor and with the α IIb chain (CD41) to form the gpIIb/IIIa complex. Both receptors mediate adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, and von Willebrand factor. Leukocyte-endothelial adhesion is also mediated by the binding of α v β 3 integrin or vitronectin receptor to CD31 (PECAM-1). In addition, interaction of the α v β

This antibody is conjugated to BD Horizon™ BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max of 602-nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20-nm filter set. BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605-nm. Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers. BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser.

Specifications

Specifications

CD61
2C9.G2
Brilliant Violet 605
Aqueous buffered solution containing ≤0.09% sodium azide.
Hamster
IgG1, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
Itgb3; Integrin beta-3; INGRB3; Platelet glycoprotein IIIa; GP3A; GPIIIa
Affinity Purified
Mouse T-cell Hybridoma 2B4 Vitronectin Receptor
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Murine
Documents
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