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Invitrogen™ HAPLN4 Polyclonal Antibody
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Catalog No. PIPA584271
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PIPA584271 100 μL
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Catalog No. PIPA584271 Supplier Invitrogen™ Supplier No. PA584271
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGSVQYPVNR PREPCGGLGG TGSAGGGGDA NGGLRNYGYR HNAEERYDAF CF Highest antigen sequence indentity to the following orthologs: Mouse - 79%, Rat - 75%.

Hyaluronan and proteoglycan link protein 4 (HAPLN4), also known as Brain Link Protein 4 (BRAL1), is a gene located on chromosome 5q14.2, encoding a member of the link protein family that plays a crucial role in stabilizing interactions between hyaluronan and proteoglycans within the extracellular matrix. HAPLN4 is predominantly expressed in the brain, especially within the central nervous system where it contributes to the structural integrity and functional modulation of neural tissues. The protein is key in maintaining the organization of the extracellular matrix by binding hyaluronan and other matrix components, facilitating cell adhesion and signaling. This is vital for processes like neuronal migration, synapse formation, and neuronal differentiation during brain development. Variations in HAPLN4 expression or function are associated with neural developmental disorders and may influence the progression of neurodegenerative diseases due to its critical role in preserving the extracellular matrix architecture and neural connectivity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HAPLN4
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HAPLN4
Gene Accession No. Q86UW8
Gene Alias 9330174O11; Brain link protein 2; brain linked protein 2; Bral2; Hapln4; Hyaluronan and proteoglycan link protein 4; hyaluronan and proteoglycan link protein 4; LOW QUALITY PROTEIN: hyaluronan and proteoglycan link protein 4; KIAA1926; link protein 4; LOW QUALITY PROTEIN: hyaluronan and proteoglycan link protein 4; Lpr4; si:dkey-19f23.2
Gene Symbols HAPLN4
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HAPLN4. Recombinant protein control fragment (Product #RP-101567).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 404037
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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