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R&D Systems™ Harmine
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Catalog No. 507550R Shop All Novus Products
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507550R 50 mg
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Catalog No. 507550R Supplier R&D Systems™ Supplier No. 5075/50

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Description

A Tocris product, part of R&D Systems. Potent and selective DYRK1A inhibitor

Harmine is a potent and selective inhibitor of DYRK1A (IC50 values are 80, 800 and 900 nM for DYRK1A, DYRK3 and DYRK2 respectively). Inhibits DYRK1A-mediated tau phosphorylation and regulates PPARγ expression. Harmine also induces pancreatic β cell proliferation and exhibits antidiabetic activity. Orally bioavailable. Harmine has high affinity (Kd = 100 nM) for the yjdF aptamer. The riboswitch function of yjdF motif RNAs is activated by Harmine and leads to robust reporter gene expressions in B. subtilis.

Specifications

Quantity 50 mg
Product Line Tocris
Product Type Harmine
Purity >98%
Molecular Weight (g/mol) 212.25
Inhibitors Harmine

For Research Use Only

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