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Invitrogen™ HARS Polyclonal Antibody
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Catalog No. PIPA5106468
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100 μL
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PIPA5106468 100 μL
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Catalog No. PIPA5106468 Supplier Invitrogen™ Supplier No. PA5106468
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HARS.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HARS
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HARS1
Gene Accession No. P12081, Q61035
Gene Alias CMT2W; dead end homolog 1; Dnd1; FLJ20491; HARS; HARS1; HARSL; HARSL protein; HisRS; histidine translase; histidine tRNA ligase; histidine--tRNA ligase; histidine--tRNA ligase, cytoplasmic; Histidyl-tRNA synthetase; histidyl-tRNA synthetase 1; histidyl-tRNA synthetase, cytoplasmic; HRS; im:7136719; MMHRS; Unknown (protein for IMAGE:7951312); USH3B; zgc:92215
Gene Symbols HARS1
Host Species Rabbit
Immunogen A synthesized peptide derived from human HARS(Accession P12081), corresponding to amino acid residues K472-C509.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15115, 3035, 307492
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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