Invitrogen™ HARS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5145102

Catalog No. FEPA5145102

Description

Immunogen sequence: LAMNKVKKMK RYHVGKVWRR ESPTIVQGRY RE Antigen sequence identity: Mouse 88%; Rat 88%.

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is an enzyme belonging to the class II family of aminoacyl-tRNA synthetases. Functioning in the synthesis of histidyl-transfer RNA, the enzyme plays an accessory role in the regulation of protein biosynthesis. The gene is located in a head-to-head orientation with HARS on chromosome five, where the homologous genes likely share a bidirectional promoter. Mutations in this gene are associated with the pathogenesis of Perrault syndrome, which involves ovarian dysgenesis and sensorineural hearing loss. Alternative splicing results in multiple transcript variants of this gene.

Specifications

• Antigen: HARS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HARS2
• Gene Alias: 4631412B19Rik; D-tyrosyl-tRNA deacylase 1 homolog; EC 6.1.1.21; EGK_16929; HARS2; Hars2l; HARSL; HARSR; HARS-related; HisRS; histidine translase; histidine tRNA ligase 2, mitochondrial (putative); histidine-tRNA ligase homolog; Histidine--tRNA ligase-like; Histidyl-tRNA synthetase; histidyl-tRNA synthetase 2; histidyl-tRNA synthetase 2, mitochondrial; histidyl-tRNA synthetase 2, mitochondrial (putative); histidyl-tRNA synthetase 2, mitochondrial, hisRS; histidyl-tRNA synthetase-like; HO3; PRLTS2; Probable histidine--tRNA ligase, mitochondrial; probable histidyl-tRNA synthetase, mitochondrial; probable histidyl-tRNA synthetase, mitochondrial-like; putative histidyl-tRNA synthetase, mitochondrial; RGD1308426; zinc finger, matrin type 2; Zmat2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23438
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid
• Isotype: IgG

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P49590
• Gene Symbols: HARS2
• Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 140-171. Recombinant protein control fragment (Product #RP-110215).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Format: Liquid