HAT1/KAT1 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-157-0227	Bethyl Laboratories, Inc A305360AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat

Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.

Specifications

• Antigen: HAT1/KAT1
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: KAT1
• Immunogen: Between 369 and 419
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: HAT1

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: O14929, Q8BY71
• Gene ID (Entrez): 107435, 8520
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody