Invitrogen™ HAT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557817

Catalog No. PIPA557817

Description

Immunogen sequence: KFKINKQHAR RVYEILRLLV TDMSDAEQYR SYRLDIKRRL ISPYKKKQRD LAKMRKCLRP EELTNQMNQI EISMQHEQLE ESFQELVEDY RRVIERLA Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.

Specifications

• Antigen: HAT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HAT1
• Gene Alias: 2410071B14Rik; AA536933; HAT1; Hat-1; histidine aminotransferase 1; histone acetyltransferase 1; Histone acetyltransferase type B catalytic subunit; histone aminotransferase 1; KAT1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107435, 296501, 8520
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14929, Q5M939, Q8BY71
• Gene Symbols: HAT1
• Immunogen: Recombinant protein corresponding to Human HAT1. Recombinant protein control fragment (Product #RP-96077).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov