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Invitrogen™ HAT1 Recombinant Rabbit Monoclonal Antibody (7U2O3)
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Catalog No. PIMA542850
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100 μL
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PIMA542850 100 μL
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Catalog No. PIMA542850 Supplier Invitrogen™ Supplier No. MA542850
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: MCF7, U-87MG, Mouse testis, Rat thymus. The target is usually found in the following locations: Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm. Immunogen sequence: HYFLVFEKYN KDGATLFATV GYMTVYNYYV YPDKTRPRVS QMLILTPFQG QGHGAQLLET VHRYYTEFPT VLDITAEDPS KSYVKLRDFV LVKLCQDLPC FSREKLMQGF NEDMVIEAQQ KFKINKQHAR RVYEILRLLV TDMSDAEQYR SYRLDIKRRL ISPYKKKQRD LAKMRKCLRP EELTNQMNQI EISMQHEQLE E.

The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HAT1
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 7U2O3
Concentration 1.49 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HAT1
Gene Accession No. O14929, Q5M939, Q8BY71
Gene Alias 2410071B14Rik; AA536933; HAT1; Hat-1; histidine aminotransferase 1; histone acetyltransferase 1; Histone acetyltransferase type B catalytic subunit; histone aminotransferase 1; KAT1
Gene Symbols HAT1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 107435, 296501, 8520
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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