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HATH6/Protein atonal homolog 8 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981798
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50-198-1798 100 μL
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Catalog No. 50-198-1798 Supplier Bioss Supplier No. BS11937R
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Description

Rabbit Polyclonal Antibody

Basic helix-loop-helix (bHLH) transcription factors play important roles in differentiation processes during embryonic development of vertebrates. ATOH8 (MATH6) is a tissue-restricted member of the atonal superfamily of bHLH transcription factors that exhibits 43-57% identity in the bHLH domain with other mammalian atonal paralogs including the NeuroD and Neurogenin factors. In the mouse, ATOH8 has been implicated in the specification and differentiation of neuronal cell lineages in the brain and may also participate in kidney development. Recent studies show that ATOH8 is a novel component of the pancreatic transcriptional network during embryonic development and suggest a potential role as a modulator of the differentiation program initiated by the pro-endocrine factor Neurog3. It is indispensable for early embryonic development, suggesting a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.

Specifications

Antigen HATH6/Protein atonal homolog 8
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ATOH8
Gene Accession No. Q96SQ7
Gene Alias 4933425C05Rik; Ath6; Atoh8; atonal bHLH transcription factor 8; atonal homolog 6; atonal homolog 8; atonal homolog 8 (Drosophila); atonal homolog bHLH transcription factor 8; basic helix loop helix transcription factor 6; basic helix-loop-helix transcription factor 6; BHLHA21; Class A basic helix-loop-helix protein 21; hATH6; Helix-loop-helix protein hATH-6; Helix-loop-helix protein mATH-6; mATH6; Okadin; Protein atonal homolog 8; RGD1561512
Gene Symbols ATOH8
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human HATH6/Protein atonal homolog 8.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84913
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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