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Invitrogen™ HAX1 Polyclonal Antibody
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Catalog No. PIPA5115343
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100 μL
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PIPA5115343 100 μL
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Catalog No. PIPA5115343 Supplier Invitrogen™ Supplier No. PA5115343
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HAX1.

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HAX1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene Hax1
Gene Accession No. O00165, O35387, Q7TSE9
Gene Alias FLJ17042; FLJ18492; FLJ93803; Hax1; HAX-1; HCLS1 (and PKD2) associated protein; HCLS1 associated protein X-1; HCLS1 associated X-1; HCLS1-associated protein X-1; HCLSBP1; HS1 binding protein; HS1-associated protein X-1; HS1-associating protein X-1; HS1-binding protein 1; HS1BP1; HSP1BP-1; mHAX-1s; OTTHUMP00000034190; RP11-137P24.1; SCN3; SIG-111; Silg111
Gene Symbols Hax1
Host Species Rabbit
Immunogen A synthesized peptide derived from human HAX1(Accession O00165), corresponding to amino acid residues G221-F271.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10456, 23897, 291202
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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