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HB-EGF Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501985504
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100 μL
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50-198-5504 100 μL
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Catalog No. 50-198-5504 Supplier Bioss Supplier No. BS3576R
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Rabbit Polyclonal Antibody

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Specifications

Antigen HB-EGF
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene HBEGF
Gene Accession No. Q99075
Gene Alias AW047313; Diphtheria toxin receptor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor); diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); DTR; DT-R; DTS; DTSF; GFHB; Hbegf; HB-EGF; HEGFL; heparin binding EGF like growth factor; heparin binding epidermal growth factor-like growth factor; Heparin-binding EGF-like growth factor; heparin-binding epidermal -growth - like growth factor; heparin-binding epidermal growth factor; heparin-binding epidermal -growth factor; Proheparin-binding EGF-like growth factor
Gene Symbols HBEGF
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human HB-EGF/DTSF.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1839
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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