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Invitrogen™ HBA1/HBA2 Polyclonal Antibody
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Catalog No. PIPA5143842
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100 μg
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PIPA5143842 100 μg
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Catalog No. PIPA5143842 Supplier Invitrogen™ Supplier No. PA5143842
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Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human placenta tissue, mouse heart tissue. IHC: human gastric signet ring cell carcinoma tissue, human rectal moderately differentiated adenocarcinoma tissue, human spleen tissue, human renal cancer tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HBA1/HBA2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene Hba1
Gene Accession No. P69905
Gene Alias alpha globin; alpha one globin; alpha-2 globin; alpha-2 globin chain; alpha-globin; delta globin; HBA1; HBA2; HBA-T2; HBA-T3; HBH; hemoglobin alpha 1 globin chain; hemoglobin alpha chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin subunit alpha 2; hemoglobin, alpha 1; hemoglobin, alpha 2; mutant hemoglobin alpha 2 globin chain
Gene Symbols Hba1, Hba2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence of human Hemoglobin/HBA1/HBA2 (AVHASLDKFLASVSTVLTSKYR).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3039, 3040
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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