Invitrogen™ HBEGF Recombinant Rabbit Monoclonal Antibody (9C2M6)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535148

Catalog No. PIMA535148

Description

Immunogen sequence: LLPLGGGRDR KVRDLQEADL DLLRVTLSSK PQALATPNKE EHGKRKKKGK GLGKKRDPCL RKYKDFCIHG ECKYVKELRA PSCICHPGYH GERCHGLSLP V.

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Specifications

• Antigen: HBEGF
• Classification: Recombinant Monoclonal
• Concentration: 0.52 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q06175, Q06186, Q99075
• Gene Symbols: HBEGF
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 50-150 of human HB-EGF (Q99075).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 9C2M6
• Conjugate: Unconjugated
• Gene: HBEGF
• Gene Alias: AW047313; Diphtheria toxin receptor; Diphtheria toxin receptor (heparin binding epidermal growth factor - like growth factor); diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); DTR; DT-R; DTS; DTSF; GFHB; hb egf; HBEGF; Hb-egf; Hegfl; heparin binding EGF like growth factor; heparin binding epidermal growth factor-like growth factor; heparin-binding EGF-like growth factor; heparin-binding epidermal -growth - like growth factor; heparin-binding epidermal growth factor; heparin-binding epidermal -growth factor; proheparin-binding EGF-like growth factor
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15200, 1839, 25433
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid