HBEGF Mouse anti-Human, Clone: OTI10A4, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0900	100 μg

Catalog No. 50-167-0900 Supplier OriGene Supplier No. CF812463

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.

Specifications

• Antigen: HBEGF
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI10A4
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: HBEGF
• Gene Accession No.: Q99075
• Gene Alias: DTR, DTS, DTSF, HEGFL
• Gene Symbols: HBEGF
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 20-208 of human HBEGF produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 1839
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1