HBG1 Mouse anti-Human, Clone:M2, Abnova™

Catalog No.	Quantity
89-333-051	100 μg

Catalog No. 89-333-051 Supplier Abnova Corporation Supplier No. H00003047M02

Description

Mouse monoclonal antibody raised against a full-length recombinant HBG1.

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5′-epsilon -- gamma-G -- gamma-A -- delta -- beta--3′. [provided by RefSeq]

Specifications

• Antigen: HBG1
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: M2
• Conjugate: Unconjugated
• Description: hemoglobin, gamma A
• Formulation: PBS with no preservative; pH 7.4
• Gene: HBG1
• Gene Accession No.: BC010913
• Gene Alias: HBGA, HBGR, HSGGL1, PRO2979
• Gene Symbols: HBG1
• Host Species: Mouse
• Immunogen: HBG1 (AAH10913, 1 a.a. ∽ 147 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3047
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Isotype: IgG1 κ