Invitrogen™ HBG2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5107140

Catalog No. PIPA5107140

Description

Sequence homology: Cow: 100%; Dog: 77%; Goat: 100%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 93%; Rabbit: 75%; Rat: 83%; Sheep: 100%.

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Specifications

• Antigen: HBG2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HBG2
• Gene Alias: abnormal hemoglobin; basic fibroblast growth factor; bFGF; Fgf2; Fgf-2; Fgfb; fibroblast growth factor 2; gamma-2-globin; G-gamma globin Paulinia; Hb F Ggamma; HBG2; HBGF-2; HBG-T1; hemoglobin gamma-2 chain; Hemoglobin gamma-G chain; hemoglobin subunit gamma 2; hemoglobin subunit gamma-2; hemoglobin, gamma G; heparin-binding growth factor 2; methemoglobin; TNCY
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3048
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P69892
• Gene Symbols: HBG2
• Immunogen: Synthetic peptide located within the following region: MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov