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Invitrogen™ HBG2 Polyclonal Antibody
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Catalog No. PIPA5107140
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100 μL
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PIPA5107140 100 μL
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Catalog No. PIPA5107140 Supplier Invitrogen™ Supplier No. PA5107140
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Description

Rabbit Polyclonal Antibody

Sequence homology: Cow: 100%; Dog: 77%; Goat: 100%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 93%; Rabbit: 75%; Rat: 83%; Sheep: 100%.

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HBG2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
Gene HBG2
Gene Accession No. P69892
Gene Alias abnormal hemoglobin; basic fibroblast growth factor; bFGF; Fgf2; Fgf-2; Fgfb; fibroblast growth factor 2; gamma-2-globin; G-gamma globin Paulinia; Hb F Ggamma; HBG2; HBGF-2; HBG-T1; hemoglobin gamma-2 chain; Hemoglobin gamma-G chain; hemoglobin subunit gamma 2; hemoglobin subunit gamma-2; hemoglobin, gamma G; heparin-binding growth factor 2; methemoglobin; TNCY
Gene Symbols HBG2
Host Species Rabbit
Immunogen Synthetic peptide located within the following region: MGNPKVKAHG KKVLTSLGDA IKHLDDLKGT FAQLSELHCD KLHVDPENFK.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3048
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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