HBO Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A302224A

Catalog No. 50-156-2070

Description

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections. Based on 100% sequence identity, this antibody is predicted to react with Rat

Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription. {ECO:0000269; PubMed:10438470, ECO:0000269; PubMed:10930412, ECO:0000269; PubMed:11278932, ECO:0000269; PubMed:16387653}.

Specifications

• Antigen: HBO
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KAT7
• Gene Alias: Histone acetyltransferase MYST2; EC 2.3.1.48; MYST protein 2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; Histone acetyltransferase binding to ORC1; MYST2; HBO1; HBOa
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11143, 217127
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.2 mg/ml
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: O95251, Q5SVQ0
• Gene Symbols: KAT7
• Immunogen: Between 125 and 175
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG