HBS1L Monoclonal Antibody (OTI1G7), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA800608

Catalog No. 50-167-8443

Description

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Specifications

• Antigen: HBS1L
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9Y450
• Gene Symbols: HBS1L
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-260 of human HBS1L produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1G7
• Conjugate: Unconjugated
• Gene: HBS1L
• Gene Alias: EF-1a, ERFS, HBS1, HSPC276, eRF3c
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10767
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid