Invitrogen™ HBS1L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587584

Catalog No. PIPA587584

Description

Immunogen sequence: MARHRNVRGY NYDEDFEDDD LYGQSVEDDY CISPSTAAQF IYSRRDKPSV EPVEEYDYED LKESSNSVSN HQLSGFDQAR LYSCLDHMRE VLGDAVPDEI LIEAVLKNKF DVQKALSGVL EQDRVQSLKD KNEATVSTGK IAKGKPVDSQ TSRSESEIVP KVAKMTVSGK KQTMGFEVPG VSSEENGHSF HTPQKGPPIE DAIASSDVLE TASKSANPPH TIQASEEQSS TPAPVKKSGK LRQQIDVKAE LEKRQGGKQL; Positive Samples: NIH/3T3, Mouse pancreas.

This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues with the highest expression in heart and skeletal muscle. The intergenic region of this gene and the MYB gene has been identified to be a quantitative trait locus (QTL) controlling fetal hemoglobin level, and this region influnces erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content. DNA polymorphisms at this region associate with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Specifications

• Antigen: HBS1L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HBS1L
• Gene Alias: 2810035F15Rik; AI326327; EF-1a; eRF3 family member; eRF3c; ERF3-similar protein; ERFS; eukaryotic release factor 3; Hbs1; HBS1 like translational GTPase; HBS1L; Hbs1-like (S. cerevisiae); HBS1-like protein; HBS1-like translational GTPase; Hsp70 subfamily B suppressor 1-like protein; HSPC276; Kiaa1038
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10767, 56422
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.06 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q69ZS7, Q9Y450
• Gene Symbols: HBS1L
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human HBS1L (NP_0066111).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG