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Invitrogen™ HCCS Polyclonal Antibody
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Catalog No. PIPA551783
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100 μL
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PIPA551783 100 μL
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Catalog No. PIPA551783 Supplier Invitrogen™ Supplier No. PA551783
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YVECPIRGTA AENKENLDPS NLMPPPNQTP APDQPFALST VREESSIPRA DSEKKWVYPS EQMFWNAMLK KGWKWKDEDI SQKDMYNIIR IHNQNNEQAW KEILKWEALH AAECPCGPSL IRFGGKAKEY SPRARIRSWM GYEL Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 92%.

CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268 amino acid mitochondrial inner membrane protein that belongs to the cytochrome c-type heme lyase family. Containing two HRM (heme regulatory motif) repeats, HCCS participates in the covalent linkage of a heme group to an apoprotein of cytochrome c. The gene encoding HCCS maps to the human X chromosome. Defects to this gene cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS). MCOPS7 is an X-linked male-lethal disorder that results in eye deformation, unilateral or bilateral microphthalmia, linear skin defects in affected females, and in utero lethality for males.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HCCS
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HCCS
Gene Accession No. P53701, P53702
Gene Alias CCHL; cytochrome c heme-lyase; cytochrome c-type heme lyase; HCCS; holocytochrome c synthase; holocytochrome c synthetase; holocytochrome c-type synthase; LSDMCA1; MCOPS7; microphthalamia with linear skin defects; MLS; RGD1563855
Gene Symbols HCCS
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HCCS. Recombinant protein control fragment (Product #RP-92157).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15159, 3052, 317444
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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