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Invitrogen™ HCCS Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA575378
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268 amino acid mitochondrial inner membrane protein that belongs to the cytochrome c-type heme lyase family. Containing two HRM (heme regulatory motif) repeats, HCCS participates in the covalent linkage of a heme group to an apoprotein of cytochrome c. The gene encoding HCCS maps to the human X chromosome. Defects to this gene cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS). MCOPS7 is an X-linked male-lethal disorder that results in eye deformation, unilateral or bilateral microphthalmia, linear skin defects in affected females, and in utero lethality for males.
Specifications
HCCS | |
Polyclonal | |
Unconjugated | |
HCCS | |
CCHL; cytochrome c heme-lyase; cytochrome c-type heme lyase; HCCS; holocytochrome c synthase; holocytochrome c synthetase; holocytochrome c-type synthase; LSDMCA1; MCOPS7; microphthalamia with linear skin defects; MLS; RGD1563855 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
15159, 3052, 317444 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 0.05% sodium azide; pH 7.2 | |
P53701, P53702 | |
HCCS | |
Synthetic peptide corresponding to amino acids 80-120 of Human HCCS. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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