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HCF-1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988026
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50-198-8026 100 μL
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Catalog No. 50-198-8026 Supplier Bioss Supplier No. BS7803R
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Description

Rabbit Polyclonal Antibody

Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a NF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-kappa-B activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.

Specifications

Antigen HCF-1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene HCFC1
Gene Accession No. P51610
Gene Alias AW060991; C1 factor; CFF; HCF; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6; HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF1; HCF-1; HCFC1; HFC1; Host cell factor 1; host cell factor C1; host cell factor C1 (VP16-accessory protein); LOC100352051; LOW QUALITY PROTEIN: host cell factor 1; MRX3; PPP1R89; protein phosphatase 1, regulatory subunit 89; RGD1563804; VCAF; VP16 accessory protein; VP16-accessory protein
Gene Symbols HCFC1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human HCF-1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3054
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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