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Invitrogen™ HCFC1 Polyclonal Antibody
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Catalog No. PIPA5102495
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100 μL
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PIPA5102495 100 μL
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Catalog No. PIPA5102495 Supplier Invitrogen™ Supplier No. PA5102495
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total HCFC1.

Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a NF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-kappa-B activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HCFC1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene HCFC1
Gene Accession No. P51610, Q61191
Gene Alias AW060991; C1 factor; CFF; HCF; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6; HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF1; HCF-1; hcfc1; HFC1; host cell factor 1; host cell factor C1; host cell factor C1 (VP16-accessory protein); LOW QUALITY PROTEIN: host cell factor 1; MRX3; PPP1R89; protein phosphatase 1, regulatory subunit 89; RGD1563804; VCAF; VP16 accessory protein; VP16-accessory protein
Gene Symbols HCFC1
Host Species Rabbit
Immunogen A synthesized peptide derived from human HCFC1(Accession P51610), corresponding to amino acid residues R200-V250.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15161, 3054, 363519
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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