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hCG beta Antibody Cocktail, Invitrogen™

Catalog No. PIMA511324
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PIMA511324 500 μL
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Catalog No. PIMA511324 Supplier Thermo Scientific Supplier No. MA511324

Description

Antibody Cocktail

MA5-11324 targets Chorionic Gonadotropin Human in IHC (P) applications and shows reactivity with Human samples. The MA5-11324 immunogen is purified beta-subunit of HCG.

hCG beta is the beta chain of hCG (Human chorionic gonadotropin), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. hCG is made up of alpha and beta subunits that are non-covalently associated. The alpha subunit is similar to those found on the pituitary hormones FSH, LH ans TSH. However, the beta subunit is different in FSH, LH and TSH and are involved in conferring biological specificity. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and Beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). Diseases associated with Hcg dysfunction include gestational trophoblastic tumor and hydatidiform mole, recurrent 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen hCG beta
Applications Immunohistochemistry (Paraffin)
Classification Cocktail
Clone CG04, CG05
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene CGB3
Gene Accession No. P0DN86
Gene Alias CGB; CGB3; CGB5; CGB7; CGB8; CG-beta; Choriogonadotropin subunit beta; choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit; chorionic gonadotropin beta subunit 3; chorionic gonadotropin chain beta; chorionic gonadotropin human; chorionic gonadotropin, beta polypeptide; FSH-alpha; hCGB; human chorionic gonadotropin; LSH-alpha; TSH-alpha
Gene Symbols CGB3
Host Species Mouse
Immunogen Purified beta-subunit of HCG
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1082
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1 κ, IgG2a κ
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