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hCG beta Monoclonal Antibody (P3G7), Invitrogen™

Catalog No. PIMA514681
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100 μg
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Catalog No. Quantity
PIMA514681 100 μg
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Catalog No. PIMA514681 Supplier Thermo Scientific Supplier No. MA514681

Description

Mouse Monoclonal Antibody

MA5-14681 targets Chorionic Gonadotropin in ELISA, IP, and RIA applications and shows reactivity with Human samples. The MA5-14681 immunogen is chorionic Gonadotropin, -Subunit. MA5-14681 detects Chorionic Gonadotropin which has a predicted molecular weight of approximately 13 kDa. Product MA514681 is a smaller package size of MIH9830 (formerly sold as a Seradyn product).

hCG beta is the beta chain of hCG (Human chorionic gonadotropin), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. hCG is made up of alpha and beta subunits that are non-covalently associated. The alpha subunit is similar to those found on the pituitary hormones FSH, LH ans TSH. However, the beta subunit is different in FSH, LH and TSH and are involved in conferring biological specificity. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and Beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). Diseases associated with Hcg dysfunction include gestational trophoblastic tumor and hydatidiform mole, recurrent 1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen hCG beta
Applications ELISA, Immunoprecipitation, Radioimmune Assays (RIA)
Classification Monoclonal
Clone P3G7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene CGB3
Gene Accession No. P0DN86
Gene Alias CGB; CGB3; CGB5; CGB7; CGB8; CG-beta; Choriogonadotropin subunit beta; choriogonadotropin subunit beta 3; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin beta subunit; chorionic gonadotropin beta subunit 3; chorionic gonadotropin chain beta; chorionic gonadotropin human; chorionic gonadotropin, beta polypeptide; FSH-alpha; hCGB; human chorionic gonadotropin; LSH-alpha; TSH-alpha
Gene Symbols CGB3
Host Species Mouse
Immunogen Chorionic Gonadotropin, -Subunit
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1082
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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WARNING: Cancer - www.P65Warnings.ca.gov
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