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Invitrogen™ HCN4 Monoclonal Antibody (N114/10), FITC
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Catalog No. PIMA545432
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100 μg
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Catalog No. Quantity
PIMA545432 100 μg
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Catalog No. PIMA545432 Supplier Invitrogen™ Supplier No. MA545432
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45432 was sufficient for detection of HCN4 in 10 μg of COS cell lysate transiently transfected with HCN4 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 130kDa. No cross-reactivity against other HCNs.

HCN4 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HCN4
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry, Microarray
Classification Monoclonal
Clone N114/10
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS, 9.09mM sodium bicarbonate with 640.91mM DMSO, 136.36mM ethanolamine and no preservative; pH 7.4
Gene Hcn4
Gene Accession No. O70507, Q9JKA7, Q9TV66, Q9Y3Q4
Gene Alias Bcng3; BCNG-3; brain cyclic nucleotide-gated channel 3; Hcn3; Hcn4; hyperpolarization activated cyclic nucleotide gated potassium channel 4; hyperpolarization activated cyclic nucleotide-gated cation channel 4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; hyperpolarization-activated, cyclic nucleotide-gated K+ 3; hyperpolarization-activated, cyclic nucleotide-gated K+ 4; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4; SSS2
Gene Symbols Hcn4
Host Species Mouse
Immunogen Fusion protein amino acids 1019-1198 (c-terminus) of rat HCN4.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009452, 10021, 330953, 59266
Target Species Human, Mouse, Rat, Rabbit
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1
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