Invitrogen™ HDAC1 Recombinant Rabbit Monoclonal Antibody (2L6O7)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA534962

Catalog No. PIMA534962

Description

Immunogen sequence: MTNQNTNEYL EKIKQRLFEN LRMLPHAPGV QMQAIPEDAI PEESGDEDED DPDKRISICS SDKRIACEEE FSDSEEEGEG GRKNSSNFKK AKRVKTEDEK E.

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.

Specifications

• Antigen: HDAC1
• Classification: Recombinant Monoclonal
• Concentration: 0.4 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O09106, Q13547, Q4QQW4
• Gene Symbols: HDAC1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 350-450 of human HDAC1 (Q13547).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 2L6O7
• Conjugate: Unconjugated
• Gene: HDAC1
• Gene Alias: DKFZp686H12203; GON-10; HD1; Hdac1; Hdac1-ps; Histone deacetylase 1; histone deacetylase 1-like protein; MommeD5; reduced potassium dependency, yeast homolog-like 1; RP4-811H24.2; RPD3; RPD3L1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 297893, 3065, 433759
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid