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Invitrogen™ HDAC1 Monoclonal Antibody (CL0510)
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Catalog No. PIMA534985
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100 μL
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Catalog No. Quantity
PIMA534985 100 μL
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Catalog No. PIMA534985 Supplier Invitrogen™ Supplier No. MA534985
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Description

Mouse Monoclonal Antibody

Immunogen sequence: RIACEEEFSD SEEEGEGGRK NSSNFKKAKR VKTEDEKEKD PEEKKEVTEE EKTKEEKPEA KGVKE Highest antigen sequence indentity to the following orthologs: Rat - 98%, Mouse - 98%.

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HDAC1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone CL0510
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HDAC1
Gene Accession No. O09106, Q13547, Q4QQW4
Gene Alias DKFZp686H12203; GON-10; HD1; Hdac1; Hdac1-ps; Histone deacetylase 1; histone deacetylase 1-like protein; MommeD5; reduced potassium dependency, yeast homolog-like 1; RP4-811H24.2; RPD3; RPD3L1
Gene Symbols HDAC1
Host Species Mouse
Immunogen Recombinant protein fragment of Human HDAC1 (Product #RP-95336)
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 297893, 3065, 433759
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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