Invitrogen™ HDAC2 Polyclonal Antibody, Alexa Fluor™ 647

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1861A647

Catalog No. PIPA1861AY

Description

PA1861A647 detects histone deacetylase 2 (HDAC2) from canine, hamster, human, mouse, non-human primate, rat tissues and cells. The PA1861A647 immunogen is a synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2. This immunizing peptide (Cat. # PEP-070) is available for use in neutralization and control experiments.

HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: HDAC2
• Classification: Polyclonal
• Conjugate: Alexa Fluor 647
• Gene: HDAC2
• Gene Alias: D10Wsu179e; HD2; hdac 2; Hdac2; hdac-2; Histone deacetylase 2; histone deacetylase 2-like protein; histone deacetylase-2; I79_010219; mRPD3; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 transcription factor-binding protein; YY1-associated factor 1; Yy1bp
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100764557, 15182, 3066, 475035, 84577
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P70288, Q92769
• Gene Symbols: HDAC2
• Immunogen: Synthetic peptide corresponding to residues C T(475) D T K G T K S E Q L S N P(488) of human HDAC2.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Canine, Monkey, Hamster
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov