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HDAC3 Monoclonal Antibody (3G6), Active Motif™
SDP

Catalog No. 501992802
Encompass
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50-199-2802 10 μg
50-199-2801 100 μg
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Catalog No. 50-199-2802 Supplier Active Motif Supplier No. 39718
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Description

Mouse Monoclonal Antibody

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Specifications

Antigen HDAC3
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 3G6
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene HDAC3
Gene Accession No. O15379
Gene Alias AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; Histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
Gene Symbols HDAC3
Host Species Mouse
Immunogen This HDAC3 antibody was raised against a synthetic peptide corresponding to amino acids 411-428 of human HDAC3.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8841
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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