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HDAC3 Monoclonal Antibody (OTI4E10), TrueMAB™, OriGene
SDP

Catalog No. 501681002
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100 μL
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Catalog No. Quantity
50-168-1002 100 μL
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Catalog No. 50-168-1002 Supplier OriGene Supplier No. TA806191
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Description

Mouse Monoclonal Antibody

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Specifications

Antigen HDAC3
Applications Western Blot
Classification Monoclonal
Clone OTI4E10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene HDAC3
Gene Accession No. O15379
Gene Alias HD3, RPD3, RPD3-2
Gene Symbols HDAC3
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-235 of human HDAC3 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8841
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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