HDAC3 Monoclonal Antibody (OTI4E10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA806191

Catalog No. 50-168-1002

Description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Specifications

• Antigen: HDAC3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O15379
• Gene Symbols: HDAC3
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-235 of human HDAC3 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot
• Clone: OTI4E10
• Conjugate: Unconjugated
• Gene: HDAC3
• Gene Alias: HD3, RPD3, RPD3-2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8841
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid