HDAC3 Mouse anti-Human, Clone: OTI4E10, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF806191

Catalog No. 50-166-7727

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.

Specifications

• Antigen: HDAC3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: HDAC3
• Gene Alias: HD3, RPD3, RPD3-2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8841
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI4E10
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O15379
• Gene Symbols: HDAC3
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-235 of human HDAC3 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a