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Invitrogen™ HDAC3 Polyclonal Antibody
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Catalog No. PIPA5120454
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100 μL
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PIPA5120454 100 μL
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Catalog No. PIPA5120454 Supplier Invitrogen™ Supplier No. PA5120454
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Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, K-562, NIH/3T3, Mouse brain, Mouse spleen, Rat kidney. The target is usually found in the following locations: Cytoplasm, Nucleus, cytosol. Immunogen sequence: FEYFAPDFTL HPDVSTRIEN QNSRQYLDQI RQTIFENLKM LNHAPSVQIH DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HDAC3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene HDAC3
Gene Accession No. O15379, O88895, Q6P6W3
Gene Alias AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
Gene Symbols HDAC3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 329-428 of human HDAC3 (NP_0038742).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15183, 84578, 8841
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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