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Invitrogen™ HDAC3 Recombinant Rabbit Monoclonal Antibody (1M1O7)
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Catalog No. PIMA542703
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100 μL
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PIMA542703 100 μL
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Catalog No. PIMA542703 Supplier Invitrogen™ Supplier No. MA542703
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: PC-3, HeLa, Mouse brain, NIH/3T3, Rat testis. The target is usually found in the following locations: Cytoplasm, Nucleus, cytosol. Immunogen sequence: FEYFAPDFTL HPDVSTRIEN QNSRQYLDQI RQTIFENLKM LNHAPSVQIH DVPADLLTYD RTDEADAEER GPEENYSRPE APNEFYDGDH DNDKESDVEI.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. HDAC3 belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HDAC3
Applications ELISA, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone 1M1O7
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HDAC3
Gene Accession No. O15379, O88895, Q6P6W3
Gene Alias AW537363; HD3; Hdac3; HDAC3 splicing HDAC3alpha; HDAC3 splicing HDAC3beta; HDAC3 splicing HDAC3delta; HDAC3 splicing HDAC3gamma; histone deacetylase 3; histone deacetylase 3-like protein; RPD3; RPD3-2; SMAP45
Gene Symbols HDAC3
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 329-428 of human HDAC3 (NP_0038742).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15183, 84578, 8841
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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